Peer-reviewed · E. coli
Physical cell disruption observed by SEM
E. coli cells on the diamond nanospike surface are severely disrupted, consistent with a mechanical “ripping” model.
Open study →Evidence
Claims grounded in data
Addrix has peer-reviewed laboratory evidence against E. coli, qualitative long-duration observations, SEM evidence of cell disruption and a Tetrivex-owned intellectual property foundation. Addrix is adding application-specific validation on top of that foundation.
Surface morphology
The architecture matters
In quantitative testing, silicon and non-nanostructured polycrystalline diamond showed pronounced E. coli growth, supporting the role of nanospike topography in the observed antibacterial behavior.
Review methods & Figure 3 →What the study supports
Demonstrated performance
in laboratory settings.
The published study reports measurable antibacterial behavior and direct SEM evidence of cell disruption under defined laboratory conditions. Results are presented in the context of the tested surfaces, organisms and methods.
E. coliQuantitative antibacterial testing included multiple diamond nanospike samples and comparison materials.
48 / 96 hQualitative mixed-organism collections showed no observable growth on the nanospike surface at these post-exposure timepoints.
7 yearsA sample synthesized seven years before testing retained consistent antimicrobial behavior in the reported study.
Intellectual property
Tetrivex-owned IP.
Built for commercialization.
Tetrivex Materials owns and controls intellectual property associated with the Addrix nanostructured surface technology and manages the rights used in commercial development and licensing.
Technical details and application-specific licensing terms are shared with qualified partners through the appropriate evaluation and confidentiality process.
Discuss a partnershipAdditional validation
Extending the evidence base.
Addrix has demonstrated laboratory performance against E. coli. Tetrivex Materials is pursuing additional independent testing across representative substrates, organisms, cleaning protocols and mechanical-use conditions to support application-specific antibacterial and broader antimicrobial claims.
Validation roadmap
What comes
next.
Each commercial field of use is open to exclusive rights upon entering a partnership to demonstrate the following:
01
Representative substrate testing
Confirm deposition, adhesion, morphology and repeatability on the actual OEM material system.
02
Durability & cleaning exposure
Test wiping, cleaning agents, abrasion, impact and other mechanical conditions relevant to the component.
03
Independent biological validation
Expand organism panels and use defined methods appropriate to the intended antibacterial or antimicrobial claim.
04
Claim & regulatory definition
Match public claims to the final data package and market-specific regulatory requirements.
Source
Peer-reviewed reference.
Public performance claims presented here are grounded in the peer-reviewed study below.
Peer-reviewed paperPaxton et al., “A scalable approach to topographically mediated antimicrobial surfaces based on diamond,” Journal of Nanobiotechnology 19, 458 (2021).Open ↗